Ariheet Pharmachem LLP

API Name: Doxylamine Succinate

Pharmaceutical Category: First-generation antihistamine (H1 receptor antagonist)

Therapeutic Uses:

• Short-term management of insomnia (sleep aid)

• Relief of symptoms of allergic rhinitis (sneezing, runny nose, itching)

• Prevention and treatment of nausea and vomiting (often combined with pyridoxine in pregnancy-related nausea)

IUPAC Name: N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine hydrogen butanedioate

Molecular Formula: C₂₁H₂₈N₂O₅

Molecular Weight: 388.46 g/mol

CAS Number: 562-10-7

Appearance: White to off-white crystalline powder

Solubility: Freely soluble in water and ethanol

Melting Point: ~106–109 °C

Stability: Stable under recommended storage; hygroscopic, protect from moisture

Available Grades:

• IP (Indian Pharmacopoeia)

• BP (British Pharmacopoeia)

• USP (United States Pharmacopeia)

• EP (European Pharmacopoeia)

Purity: ≥ 99% (on dry basis)

Impurities: Controlled within pharmacopeial specifications

Packaging: 1kg / 5kg / 25kg HDPE drum or fiber drum, double polybag inside

Storage Conditions: Store in a cool, dry place, protected from light and moisture; tightly sealed container recommended

Active Pharmaceutical Ingredients (APIs)

Antihistamines

Sedatives & Hypnotics

Anti-allergic & Anti-nausea Drugs